Transition from academia to industry - a tale of many tales

You might be just one step away from industry opportunities

Transition from academia to industry - a tale of many tales

Recently, I attended an event where postdocs from several academic institutions came to the company for a day of seminars, lab tours, and a networking lunch. I was one of the hosts for the computational science table.

After exchanging pleasantries, questions started flowing. It is indeed a difficult period for academic postdocs who would like to try out industry, even harder for people who need sponsorships. However, I did see a glimmer of hope, as there are so many skills and opportunities around them that can perhaps help them make the transition, when they can actually discover them. I’m sharing three examples where I hope I helped them see a path forward.

“A” was a bit confused, uncertain where she would fit in. She was an immunologist at the bench, and recently switched to data curation for immune assays across institutions and fields. She needs to make sure that results can be entered into a large database with a predefined ontology. She’s no longer doing experiments and not sure if industry needs her data curation skills learned from work rather than from an academic program. I asked her, do you know how the data are used downstream? I was a bit surprised she didn’t, since those standardized data can have so many applications downstream, like meta-analysis and even AI agents that can traverse the entire database and offer previously impossible insights. So I suggested that she reach out to colleagues using the data to learn more, and express interest for getting involved. With her immunology expertise, she can ask and answer questions that others without her background cannot. Once she learns more about how to use the data, even some coding with the help of AI, she would fit the bill for a translational scientist or even data scientist within a therapeutic area. More likely than not, she has the environment to learn, and she seems just one step away from various industry opportunities.

“B” is a pure computational biologist analyzing multi-omic data. She sometimes has trouble understanding technical terms discussed by bench scientists during lab meetings, such as the design of yeast display libraries for antibody discovery. I suggested that she directly reach out to her colleagues working in the lab on this exact topic. Of course, she needs to prepare in advance by reading foundational papers for this technology, so she can ask specific questions. By doing so, she can demonstrate two things: 1) she wants to understand the experimental design and is willing to get involved earlier on, rather than waiting for the data to be delivered to her to analyze, only to find out that insufficient data quality or replicates hinders the ability to get a clear answer, which can be avoided if she participates in experimental design; 2) she shows that she’s willing to communicate with the bench scientists in their language, and offers analytical help whenever they need it, a win-win situation here. In an academic lab, dry and wet lab scientists are typically right around one another, unlike in the industry where the teams doing dry and wet lab work can be at two different sites. It’s a golden opportunity and invaluable resource right at their fingertips, yet one that most graduate students fail to recognize or take advantage of.

We then only had ten minutes left, and “C” introduced herself. She designed an entire bioinformatic pipeline for processing epitope sequencing data (can’t quite recall the details), and switched to a hybrid bench scientist who does experiments and analyzes the data at the same time. This is such a rare career transition - I’ve only seen people transition from wet lab to dry, almost never the other way around. She said she enjoys it because she gets to design her own experiments that test hypotheses she generates from in silico analysis. I encouraged her to keep going, and keep up with her communication skills, because she can speak two different languages and serve as the perfect bridge between the bench and computer, a unique advantage. She will be an asset wherever she goes.

I truly enjoy learning about individual journeys and trying to help a talent fulfill their best potential. If you’d like to chat, please reach out, would love to help!

Xin Huang

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Hi! With more than 13 years of hands-on bioinformatics experiences, I have tackled multi-omics analysis including single-cell RNA-Seq, bulk RNA-Seq, proteomics, genomics and amplicon sequencing. Starting from the academia, I have gone through a rigorous PhD education, a postdoc training with in vivo expertise, worked in an academic lab blending industrial operation, and finally into the industry working as a computational biologist and most recently, a translational scientist specializing in CNS biomarker discovery. I am transitioning from a traditional computational biologist, sinking my teeth into bioinformatics projects, to a more strategic translational scientist, collaborating with cross-functional colleagues, including bench scientists, data scientists, clinical scientists, and external academic partners. The key here, as I am gradually figuring out, is the ability to understand the biological context and impact of a particular project, and bring in a diverse panel of experts to leverage their domain expertise towards a mutual goal. One of my passions is to help junior colleagues/scientists grow. I genuinely enjoy seeing mentees achieve their potential and grow to their better selves. I have mentored interns, contractors, junior colleagues and undergraduate and graduate students over the years. What I find particularly fulfilling is to hear the stories of the mentees and learn about their journeys, so I can find a path tailored for their needs. Nothing else is more rewarding than seeing the spark going off of their eyes. I look forward to being part of your career journey.

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